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Book

Hypokalemic Metabolic Alkalosis

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Hypokalemic Metabolic Alkalosis

Farah Leclercq et al.
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Excerpt

Since the first step out of the marine world, the animals had to adapt to the lack of fluid and electrolytes found in abundance in seawater. Over time these creatures have developed a kidney capable of regulating salt and water retention. It is the most distal part of the nephron that is responsible for this regulation. When defective, the mechanisms that hold the maintenance of our effective plasma volume will cause electrolytes disturbance apparently unrelated but potentially dangerous, mainly hypokalemia and metabolic alkalosis. This activity will evaluate the function of the thick ascending limb and the distal convoluted tubule as well as the connecting tubule and their principal cells.

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Conflict of interest statement

Disclosure: Farah Leclercq declares no relevant financial relationships with ineligible companies.

Disclosure: Baudouin Leclercq declares no relevant financial relationships with ineligible companies.

References

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