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Book

Histology, Basophilic Stippling

John R. Sanchez  1 , David T. Lynch  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Free Books & Documents
Book

Histology, Basophilic Stippling

John R. Sanchez et al.
Free Books & Documents

Excerpt

Basophilic stippling is one example of several clinically significant erythrocyte inclusions identified on peripheral blood smears. The presence of basophilic stippling is attributed to aggregates of ribosomes or fragments of ribosomal RNA precipitated throughout the cytoplasm of circulating erythrocytes. This finding is associated with acquired and heritable hematologic disorders affecting erythropoiesis and erythrocyte maturation.

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Conflict of interest statement

Disclosure: John Sanchez declares no relevant financial relationships with ineligible companies.

Disclosure: David Lynch declares no relevant financial relationships with ineligible companies.

References

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    1. Chan NCN, Chan KP. Coarse basophilic stippling in lead poisoning. Blood. 2017 Jun 15;129(24):3270. - PubMed
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