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Book

Cladribine

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Book

Cladribine

Franklyn Rocha Cabrero et al.
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Excerpt

Multiple sclerosis is an immune-mediated inflammatory demyelinating disease of the central nervous system, resulting in loss of oligodendrocytes, astroglial scarring, and axonal injury (end-stage). Disease-modifying drugs help minimize long-term disability for people with multiple sclerosis by decreasing central nervous system inflammation, reducing the frequency and severity of acute attacks, delaying disease progression, and improving the overall quality of life. This activity covers cladribine, an established oral chemotherapy agent that the FDA recently approved for relapsing multiple sclerosis.

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Conflict of interest statement

Disclosure: Franklyn Rocha Cabrero declares no relevant financial relationships with ineligible companies.

Disclosure: Elizabeth Morrison declares no relevant financial relationships with ineligible companies.

References

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