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. 2019 Nov;38(11):1104-1106.
doi: 10.1097/INF.0000000000002433.

Global Divergence From World Health Organization Treatment Guidelines for Neonatal and Pediatric Sepsis

Charlotte Jackson  1 , Yingfen Hsia  1 , Romain Basmaci  2   3 , Julia Bielicki  1   4 , Paul T Heath  1 , Ann Versporten  5 , Herman Goossens  5 , Mike Sharland  1
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Global Divergence From World Health Organization Treatment Guidelines for Neonatal and Pediatric Sepsis

Charlotte Jackson et al. Pediatr Infect Dis J. 2019 Nov.

Abstract

We used data from 2 global point prevalence surveys of antibiotic prescribing to describe the treatment of sepsis in hospitalized neonates and children. One hundred eighty-five of 824 neonates (22.5%) and 9/786 children (1.1%) received a World Health Organization-recommended first-line treatment; of the remainder, 9/639 neonates (1.4%) and 102/777 children (13.1%) received a World Health Organization-recommended second-line treatment. Reasons for this low adherence to guidance should be explored.

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