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Randomized Controlled Trial
. 2019 Aug 20;14(8):e0220799.
doi: 10.1371/journal.pone.0220799. eCollection 2019.

The efficacy of a brief intervention to reduce alcohol use in persons with HIV in South Africa, a randomized clinical trial

Diana Huis In 't Veld  1   2   3 , Chellafe Ensoy-Musoro  4 , Supa Pengpid  5   6 , Karl Peltzer  6 , Robert Colebunders  7
Affiliations
Randomized Controlled Trial

The efficacy of a brief intervention to reduce alcohol use in persons with HIV in South Africa, a randomized clinical trial

Diana Huis In 't Veld et al. PLoS One. .

Abstract

Background: Since there is a high prevalence of high risk alcohol use in patients with HIV in Africa, with negative health effects, there is a need for short interventions to reduce alcohol use.

Methods: We studied the efficacy of a short intervention aiming to reduce alcohol use based on the Information-Motivation-Behavioural Skills Model in patients with HIV with high alcohol use (measured by AUDIT). The study was performed in three outpatient clinics in South Africa. The intervention group received in one-session intervention a personalized feedback on AUDIT results trying to make people aware that they are in the medium- or high-risk drinking category. Both the intervention and the control group received a health education leaflet.

Results: A total of 560 patients participated in the study with a follow up of 1 year. There was a significant decrease in total AUDIT scores between baseline and follow up points 1 (5 months) and 2 (1 year) in both groups. There was no significant decrease between time points 1 and 2. However, between the intervention and control groups there was no difference in reduction of alcohol use to abstinence or low risk alcohol use over time as there was no difference in absolute decrease in AUDIT-score or percentage of change in AUDIT score. The intervention had no influence on the quality of life outcomes, depression scores, stigma, tobacco use, viral load and therapy adherence at both time points. In all secondary outcomes, there was no significant interaction between intervention and time.

Conclusion: The brief intervention was not successful at reducing alcohol use both 5 and 12 months after the intervention. However, there was a beneficial effect on reported hazardous or harmful alcohol use at least over a short term follow up period in both study groups. It might be that only an interview and/or the distribution of a health leaflet can be successful in reducing alcohol use but this needs to be investigated with more objective measures of alcohol use. To sustain an effect, most likely repetitive contacts with hazardous or harmful alcohol drinkers will be needed during a long follow up period.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Flowchart of participants in the trial.
Fig 2
Fig 2. AUDIT score for the different intervention groups at different time points.
AUDIT score for the different intervention groups measured at baseline and at time point 1 and at time point 2 after the intervention. Box represents first and third quartile of data. (0 = control, 1 = intervention).
Fig 3
Fig 3. AUDIT score difference between baseline and time point 1 and baseline and time point 2 for the 2 groups.
Box represents first and third quartile of data, 0 = control, 1 = intervention.
See this image and copyright information in PMC

References

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