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. 1988 Nov 11;16(21):10153-69.
doi: 10.1093/nar/16.21.10153.

The yeast ADR6 gene encodes homopolymeric amino acid sequences and a potential metal-binding domain

P J O'Hara  1 , H Horowitz, G Eichinger, E T Young
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Free PMC article

The yeast ADR6 gene encodes homopolymeric amino acid sequences and a potential metal-binding domain

P J O'Hara et al. Nucleic Acids Res. .
Free PMC article

Abstract

The ADR6 gene of Saccharomyces cerevisiae has an open reading frame which could encode a polypeptide of 1314 amino acids. The predicted mRNA encodes a protein with homopolymeric stretches of asparagine and threonine, particularly near its amino terminus and contains additional sequences consisting of polyglutamine repeats. The predicted protein also contains a potential metal binding (Cys)4-type finger near its carboxy-terminus. An ADR6/beta-galactosidase fusion protein was predominantly nuclear in location, consistent with its role as an activator of ADH2 transcription.

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References

    1. Cell. 1985 Jan;40(1):55-62 - PubMed
    1. EMBO J. 1985 Feb;4(2):465-73 - PubMed
    1. Science. 1987 Nov 6;238(4828):797-9 - PubMed
    1. Science. 1978 May 5;200(4341):494-502 - PubMed
    1. Nature. 1980 Jan 31;283(5746):445-53 - PubMed

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