Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2019 Oct:139:79-82.
doi: 10.1016/j.radonc.2019.07.023. Epub 2019 Aug 17.

A randomized trial (RAREST-01) comparing Mepitel® Film and standard care for prevention of radiation dermatitis in patients irradiated for locally advanced squamous cell carcinoma of the head-and-neck (SCCHN)

Dirk Rades  1 , Carlos A Narvaez  2 , Laura Splettstößer  2 , Claudia Dömer  2 , Cornelia Setter  3 , Christian Idel  4 , Julika Ribbat-Idel  5 , Sven Perner  6 , Tobias Bartscht  7 , Denise Olbrich  8 , Steven E Schild  9 , Jesper Carl  10
Affiliations
Randomized Controlled Trial

A randomized trial (RAREST-01) comparing Mepitel® Film and standard care for prevention of radiation dermatitis in patients irradiated for locally advanced squamous cell carcinoma of the head-and-neck (SCCHN)

Dirk Rades et al. Radiother Oncol. 2019 Oct.

Abstract

Mepitel® Film (MEP) and standard care (STD) were compared for radiation dermatitis in SCCHN patients. This trial was stopped prematurely since13/28 patients did not tolerate MEP. Grade ≥2 dermatitis: 34.8% (MEP) vs. 35.7% (STD) at 50 Gy, 65.2% vs. 59.3% at 60 Gy. MEP was unsatisfactorily tolerated and appeared not superior (NCT03047174).

Keywords: Head-and-neck cancer; Mepitel® Film; Radiation dermatitis; Randomized trial; Standard care.

PubMed Disclaimer

Publication types

Associated data