Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Aug 21:264:1925-1926.
doi: 10.3233/SHTI190716.

Improving Patient Participation in Cancer Clinical Trials: A Qualitative Analysis of HSRProj & RePORTER

Lynette Hammond Gerido  1 , Zhe He  1
Affiliations

Improving Patient Participation in Cancer Clinical Trials: A Qualitative Analysis of HSRProj & RePORTER

Lynette Hammond Gerido et al. Stud Health Technol Inform. .

Abstract

Enrollment and representativeness, in cancer trials, have been a problem resulting in studies with poor generalizability to the real-world population. This study uses qualitative analysis of two publicly available datasets (HSRProj and RePORTER) to explore funded research projects, which employ strategies at the macro, meso, and micro levels. Our research shows that although the number of projects designed to increase participation in cancer clinical trials peaked in the 2000s, most employ a single level strategy.

Keywords: Clinical Trial; Patient Selection; Qualitative Research.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. FastStats [Internet]. Center for Disease Control and Prevention (CDC) 2018. [cited 2018 Apr 26]. Available from: https://www.cdc.gov/nchs/fastats/leading-causes-of-death.htm
    1. Weinstein IB, Case K. The History of Cancer Research: Introducing an AACR Centennial Series. Cancer Res. 2008. September 1;68(17):6861–2. - PubMed
    1. Kennedy-Martin T, Curtis S, Faries D, Robinson S, Johnston J. A literature review on the representativeness of randomized controlled trial samples and implications for the external validity of trial results. Trials. 2015. November 3;16:495. - PMC - PubMed
    1. Fu S, McQuinn L, et al. Barriers to Study Enrollment in Patients With Advanced Cancer Referred to a Phase I Clinical Trials Unit. The Oncologist. 2013. December 1;18(12):1315–20. - PMC - PubMed
    1. Heller C, Balls-Berry JE, et al. Strategies addressing barriers to clinical trial enrollment of underrepresented populations: a systematic review. Contemp Clin Trials. 2014;39(2):169–182. - PMC - PubMed

LinkOut - more resources