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Case Reports
. 2013 Sep;28(5):e058.
doi: 10.5001/omj.2013.110.

Erasmus Syndrome: A Case Report of Silicosis-induced Scleroderma in a 26-year-old Male

Joydeep Ganguly  1 , Abhishek Kumar  2 , Santu Kumar Samanta  2 , Ritabrata Mitra  2 , Somenath Kundu  2
Affiliations
Case Reports

Erasmus Syndrome: A Case Report of Silicosis-induced Scleroderma in a 26-year-old Male

Joydeep Ganguly et al. Oman Med J. 2013 Sep.

Abstract

Several occupational hazards especially exposure to silica have been implicated as causal factors for the development of scleroderma-like disorders. Many case reports have documented the co-existence of silicosis and progressive systemic sclerosis in the same patient, mostly from European countries and also from Japan and the United States. We report a case of a 26-year-old male involved in stone masonry who developed silicosis-induced diffuse parenchymal lung disease and systemic sclerosis after exposure to silica dust. To our knowledge, it is the second case to be reported from India.

Keywords: Erasmus syndrome; Interstitial lung disease; Silicosis; Systemic sclerosis.

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Figures

Figure 1
Figure 1
HRCT thorax showing diffuse nodular lesions mostly in the upper and middle lobe.
Figure 2
Figure 2
Egg-shell calcification seen in the mediastinal and hilar lymph nodes.
Figure 3
Figure 3
Skin biopsy from the face showing dermal shrinkage.
See this image and copyright information in PMC

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