Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Jul 19;9(3):e2019106.
doi: 10.4322/acr.2019.106. eCollection 2019 Jul-Sep.

Death from pan-resistant superbug

Affiliations
Case Reports

Death from pan-resistant superbug

Larry Nichols. Autops Case Rep. .

Abstract

Acinetobacter baumannii has emerged as a pan-resistant superbug causing fatal infections in vulnerable patients. This report is the case of an immunosuppressed transplant patient with a fatal pneumonia due to pan-resistant Acinetobacter baumannii. Alternative therapy for resistant Acinetobacter infection is currently the subject of intense interest and research. This report illustrates the features of this type of emerging infectious disease and reviews some of the novel approaches to treatment.

Keywords: Acinetobacter; Autopsy; Drug resistance, Bacterial; Pneumonia.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None

Figures

Figure 1
Figure 1. Photomicrograph of the lung. The alveoli are filled with inflammatory cells mixed with some fibrin and a few red blood cells. Most of the inflammatory cells are macrophages (characteristic of subacute phase pneumonia), replacing neutrophils (characteristic of acute phase pneumonia) (H&E,200X).
Figure 2
Figure 2. Photomicrograph of the lung. There are large numbers of small Gram-negative coccobacilli, many of them intracellular (Brown and Brenn, 400X).

References

    1. Serifoglu I, Er Dedekarginoglu B, Savas Bozbas S, Akcay S, Haberal M. Clinical characteristics of Acinetobacter baumannii infection in solid-organ transplant recipients. Exp Clin Transplant. 2018;16(Suppl 1):171-5. - PubMed
    1. Zhou S, Fan L, Wang Z, et al. . Increasing rates of Acinetobacter baumannii infection and resistance in an oncology department. J Cancer Res Ther. 2018;14(1):68-71. 10.4103/jcrt.JCRT_737_17. - DOI - PubMed
    1. Maciel WG, Silva KE, Croda J, et al. . Clonal spread of carbapenem-resistant Acinetobacter baumannii in a neonatal intensive care unit. J Hosp Infect. 2018;98(3):300-4. 10.1016/j.jhin.2017.10.015. - DOI - PubMed
    1. Asif M, Alvi IA, Rehman SU. Insight into Acinetobacter baumannii: pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities. Infect Drug Resist. 2018;11:1249-60. 10.2147/IDR.S166750. - DOI - PMC - PubMed
    1. Vazquez Guillamet C, Kollef MH. Acinetobacter pneumonia: improving outcomes with early identification and appropriate therapy. Clin Infect Dis. 2018;67(9):1455-62. 10.1093/cid/ciy375. - DOI - PubMed

Publication types

LinkOut - more resources