Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 Aug 22;178(5):1036-1038.
doi: 10.1016/j.cell.2019.07.040.

Mammalian Mediator as a Functional Link between Enhancers and Promoters

Julie Soutourina  1
Affiliations
Free article
Comment

Mammalian Mediator as a Functional Link between Enhancers and Promoters

Julie Soutourina. Cell. .
Free article

Abstract

In this issue of Cell, Casellas and colleagues provide insights into the structural and functional aspects of the mammalian multi-subunit Mediator complex, a conserved and essential transcriptional coregulator. Combining cryo-EM, genetic, and genomic analyses, the work sheds light on Mediator's mode of action as a functional bridge between enhancers and promoters.

PubMed Disclaimer

Comment on

Substances

LinkOut - more resources