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Editorial
. 2019 Aug 15;11(8):1921.
doi: 10.3390/nu11081921.

Modulation of Gut Microbiota for Health by Current and Next-Generation Probiotics

Reetta Satokari  1
Affiliations
Editorial

Modulation of Gut Microbiota for Health by Current and Next-Generation Probiotics

Reetta Satokari. Nutrients. .

Abstract

The human gut microbiota is a complex ecosystem and has an essential role in maintaining intestinal and systemic health. Microbiota dysbiosis is associated with a number of intestinal and systemic conditions and its modulation for human health is of great interest. Gut microbiota is a source of novel health-promoting bacteria, often termed as next-generation probiotics in order to distinguish them from traditional probiotics. The previous lessons learned with traditional probiotics can help the development of next-generation probiotics that target specific health issues and needs.

Keywords: commensal bacteria; gut microbiota; human health; probiotic.

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Conflict of interest statement

The author declares no conflict of interest.

Comment on

References

    1. Lavelle A., Hill C. Gut Microbiome in Health and Disease: Emerging Diagnostic Opportunities. Gastroenterol. Clin. North Am. 2019;48:221. doi: 10.1016/j.gtc.2019.02.003. - DOI - PubMed
    1. Markowiak P., Śliżewska K. Effects of Probiotics, Prebiotics, and Synbiotics on Human Health. Nutrients. 2017;9:1021. doi: 10.3390/nu9091021. - DOI - PMC - PubMed
    1. Mättö J., Fondén R., Tolvanen T., Von Wright A., Vilpponen-Salmela T., Satokari R., Saarela M. Intestinal survival and persistence of probiotic Lactobacillus and Bifidobacterium strains administered in triple-strain yoghurt. Int. Dairy J. 2006;16:1174–1180. doi: 10.1016/j.idairyj.2005.10.007. - DOI
    1. Maldonado-Gómez M.X., Martínez I., Bottacini F., O’Callaghan A., Ventura M., van Sinderen D., Hillmann B., Vangay P., Knights D., Hutkins R.W., et al. Stable Engraftment of Bifidobacterium longum AH1206 in the Human Gut Depends on Individualized Features of the Resident Microbiome. Cell Host Microbe. 2016;20:515. doi: 10.1016/j.chom.2016.09.001. - DOI - PubMed
    1. Panigrahi P., Parida S., Nanda N.C., Satpathy R., Pradhan L., Chandel D.S., Baccaglini L., Mohapatra A., Mohapatra S.S., Misra P.R., et al. A randomized synbiotic trial to prevent sepsis among infants in rural India. Nature. 2017;548:407. doi: 10.1038/nature23480. - DOI - PubMed

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