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. 2019 Dec;41(12):4191-4198.
doi: 10.1002/hed.25926. Epub 2019 Aug 24.

Ameloblastic carcinoma: Clinicopathological analysis of 18 cases and a systematic review

Ling Deng  1   2 , Rui Wang  1 , Mingzhong Yang  3 , Wei Li  1 , Ling Zou  4
Affiliations

Ameloblastic carcinoma: Clinicopathological analysis of 18 cases and a systematic review

Ling Deng et al. Head Neck. 2019 Dec.

Abstract

Objectives: Exploring the clinicopathological features of ameloblastic carcinoma (AC) and reviewing the literature to improve the diagnosis and treatment of the disease.

Materials and methods: Clinical data and pathological features of 18 cases of AC were retrospectively analyzed. A systematic review was carried out by searching PubMed and Medline databases using the MeSH terms "ameloblastic" and "carcinoma."

Results: In the systematic analysis, 125 cases of AC from 81 eligible original studies and 18 cases of AC from this research were included. The male-to-female ratio was 2.58:1, and the mandible-to-maxilla ratio was 1.80:1. Mean age of patients was 45.3 years. Thirty-seven cases of recurrence and 27 cases of metastasis were recorded.

Conclusion: AC is a rare neoplasm of the odontogenic epithelium. A systematic review indicates that diagnoses at the early phase and a close periodic assessment for recurrence and metastasis are necessary.

Keywords: ameloblastic carcinoma; diagnosis; odontogenic tumor; pathology; survival.

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References

REFERENCES

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