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Clinical Trial
. 1988 Jul;51(7):924-8.
doi: 10.1136/jnnp.51.7.924.

Withdrawal symptoms from phenytoin, carbamazepine and sodium valproate

J S Duncan  1 , S D Shorvon, M R Trimble
Affiliations
Clinical Trial

Withdrawal symptoms from phenytoin, carbamazepine and sodium valproate

J S Duncan et al. J Neurol Neurosurg Psychiatry. 1988 Jul.

Abstract

A prospective, double-blind, placebo-controlled investigation of possible withdrawal symptoms from phenytoin, carbamazepine and sodium valproate is reported in patients with active epilepsy, on combination therapy. There was an increase in seizures on reduction and withdrawal of carbamazepine, but there was no convincing evidence of withdrawal symptoms from any of these drugs.

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References

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