Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 May 23:33:51.
doi: 10.11604/pamj.2019.33.51.14664. eCollection 2019.

Jejunal multiple perforations for combined abdominal typhoid fever and miliary peritoneal tuberculosis

Affiliations
Case Reports

Jejunal multiple perforations for combined abdominal typhoid fever and miliary peritoneal tuberculosis

Michele Grieco et al. Pan Afr Med J. .

Abstract

Typhoid fever and tuberculosis, considered rare diseases in western countries, is still considered a notable problem of health issue in developing countries. The gastrointestinal manifestations of typhoid fever are the most common and the typhoid intestinal perforation (TIP) is considered the most dangerous complication. Abdominal localization of tuberculosis is the 6th most frequent site for extra pulmonary involvement, it can involve any part of the digestive system, including peritoneum, causing miliary peritoneal tuberculosis (MPT). This is the case report of a 4 years old girl with multiple jejunal perforations in a setting of contemporary miliary peritoneal tuberculosis and typhoid fever occurred in "Hopital Saint Jean de Dieu" in Tanguietà, north of Benin. The patient was admitted in the emergency department with an acute abdomen and suspect of intestinal perforation, in very bad clinical conditions, underwent emergency laparotomy. The finding was a multiple perforations of the jejunum in a setting of combined abdominal typhoid fever and miliary peritoneal tuberculosis. Typhoid intestinal perforations and peritoneal tuberculosis are a very rare cause of non-traumatic peritonitis in western country, but still common in developing country. Considering the modern migratory flux and the diffusion of volunteer missions all around the world, the western surgeon should know this pathological entities, and the best treatments available, well known by surgeons with experience of working in developing countries. The combination of both TIP and MPT in the same patient, is a very rare finding which can worsen the outcome of the patient itself.

Keywords: Typhoid fever; abdominal tuberculosis; tuberculosis; typhoid intestinal perforation.

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Surgical findings
Figure 2
Figure 2
A) intestinal typhoid perforation; B) intestinal typhoid lesion not perforated; C) miliary peritoneal tuberculosis nodules

References

    1. Buckle GC, Walker CL, Black RE. Typhoid fever and paratyphoid fever: systematic review to estimate global morbidity and mortality for 2010. J Glob Health. 2012 Jun;2(1):010401. - PMC - PubMed
    1. Azmatullah A, Qamar FN, Thaver D, Zaidi AK, Bhutta ZA. Systematic review of the global epidemiology, clinical and laboratory profile of enteric fever. J Glob Health. 2015 Dec;5(2):020407. - PMC - PubMed
    1. Park K. Park's textbook of Preventive & Social Medicine. 19. Banarasidas Bhanot; 2007. p. 768.
    1. World Health Organization . Global tuberculosis report. 2018. Accessed Dec 21 2018.
    1. Caronna R, Boukari AK, Zaongo D, Hessou T, Gayito RC, Ahononga C, et al. Comparative analysis of primary repair vs resection and anastomosis, with laparostomy, in management of typhoid intestinal perforation: results of a rural hospital in northwestern Benin. BMC Gastroenterol. 2013 Jun 19;13:102. - PMC - PubMed

Publication types