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. 2019 May 28:33:61.
doi: 10.11604/pamj.2019.33.61.18083. eCollection 2019.

Predictors of mortality in hemodialysis patients

Rajaa Msaad  1 , Rajaa Essadik  1 , Karima Mohtadi  1 , Hasnaa Meftah  1 , Halima Lebrazi  1 , Hassan Taki  1 , Anass Kettani  1 , Ghizlane Madkouri  2 , Benyounes Ramdani  2 , Rachid Saïle  1
Affiliations

Predictors of mortality in hemodialysis patients

Rajaa Msaad et al. Pan Afr Med J. .

Abstract

Introduction: Mortality in patients with chronic renal failure is high compared to the general population. The objective of our study is to evaluate the predictive factors related to mortality in hemodialysis.

Methods: This is a retrospective study involving 126 hemodialysis patients in the Nephrology Department of Ibn Rochd Hospital, Casablanca. Data were collected between January 2012 and January 2016. For each of our patients, we analyzed demographic, clinical, biological and anthropometric data. The Kaplan-Meier method and the log-rank test were used to evaluate and compare survival curves. To evaluate the effect of predictors of mortality, we used the proportional Cox hazard model.

Results: The analysis of the results showed that the surviving patients were younger than the deceased patients (43.07±13.52 years versus 53.09±13.56 years, p=0.001). Also, the latter has a significantly lower albumin and prealbumin levels (p=0.01 and p=0.04 respectively). Overall survival was 80.2%. Cox regression analysis at age (HR=1.26, p<0.0002), inflammation (HR=1.15, p<0.03), AIP> 0.24 (HR=2.1, p<0.002) and cardiovascular disease (RR=2.91, p<0.001) were associated with global and cardiovascular mortality.

Conclusion: Our study showed that the mortality rate is high in our cohort. In addition, cardiovascular diseases, under nutrition and inflammation are predictive factors for mortality. Treatment and early management of these factors are essential for reducing morbidity and mortality.

Keywords: Mortality; and chronic renal failure; cardiovascular diseases; under nutrition.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Patient overall survival curve during follow-up period
Figure 2
Figure 2
Survival curves of hemodialysis patients according to age groups
Figure 3
Figure 3
Survival curves for cardiovascular diseases
Figure 4
Figure 4
Survival curves of hemodialysis patients according to their AIP
Figure 5
Figure 5
Survival curves of patients according to nutritional status
Figure 6
Figure 6
Survival curves of hemodialysis patients according to inflammatory status
Figure 7
Figure 7
Survival curves as a function of arterial hypertension
See this image and copyright information in PMC

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