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Case Reports
. 2019 Nov;36(6):918-921.
doi: 10.1111/pde.13939. Epub 2019 Aug 25.

The biker-glove pattern of congenital melanocytic nevi

Nicole W Kittler  1 , Erin F Mathes  1 , Veronica Kinsler  2   3 , Ilona J Frieden  1
Affiliations
Free article
Case Reports

The biker-glove pattern of congenital melanocytic nevi

Nicole W Kittler et al. Pediatr Dermatol. 2019 Nov.
Free article

Abstract

Congenital melanocytic nevi (CMN) are common birthmarks with 20% occurring on the limbs. We describe 4 patients with acral CMN with a "biker-glove" distribution with sparing of the distal digits, as has previously been described in acral infantile hemangiomas (IH). The existence of the biker-glove pattern suggests that CMN arise from early mutations in melanocyte precursors and supports the recently described Kinsler-Larue hypothesis of mesenchymal distribution of melanocyte migration occurring in a circular field from a central point. Developmental errors in mesenchymal precursors with similar migration patterns may explain this shared pattern among CMN and IH.

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References

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