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. 2020 Jan;21(1):181-185.
doi: 10.1111/tra.12689. Epub 2019 Sep 9.

Caveolae: The FAQs

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Caveolae: The FAQs

Robert G Parton et al. Traffic. 2020 Jan.

Abstract

Caveolae are an abundant, but enigmatic, plasma membrane feature of vertebrate cells. In this brief commentary, the authors attempt to answer some key questions related to the formation and function of caveolae based on round-table discussions at the first EMBO Workshop on Caveolae held in France in May 2019.

Keywords: EHD2; caveolae; caveolins; cavins; endocytosis; lipodystrophy; membrane; muscular dystrophy.

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Figures

Figure 1
Figure 1
Platinum-replica EM of the plasma membrane of cultured myotubes showing abundant caveolae; both single caveolae and caveolar clusters or rosettes (asterisks) are evident. The characteristic striped coats of caveolae can be observed at higher magnification (inset; arrowheads). Bars, main figure 1μm; inset 0.25μm.

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