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Case Reports
. 2019 Aug 26;12(8):e228882.
doi: 10.1136/bcr-2018-228882.

Cetuximab associated dermal filler reaction

Shivanshan Pathmanathan  1 , Marcin Dzienis  1
Affiliations
Case Reports

Cetuximab associated dermal filler reaction

Shivanshan Pathmanathan et al. BMJ Case Rep. .

Abstract

A 52-year-old male patient with hyaluronic acid-based dermal fillers injected in his cheeks was diagnosed with glossotonsillary malignancy, and managed with concurrent cetuximab (epidermal growth factor receptor inhibitor) and radiation therapy. He developed significant inflammation around the dermal filler sites after first cycle of cetuximab which improved with dissolution of the dermal fillers with hyaluronidase. This suggests that cetuximab can lead to inflammation around the dermal filler sites, which can be treated with dissolution of the filler.

Keywords: chemotherapy; dermatology; head and neck cancer.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Nodules and oedema can be noted around the dermal filler site.
Figure 2
Figure 2
Resolution of the nodules and oedema postadministration of hyaluronidase to dissolve the dermal fillers.
See this image and copyright information in PMC

References

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