Fractional Laser-assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review
- PMID: 31453018
- PMCID: PMC6701901
- DOI: 10.7759/cureus.4943
Fractional Laser-assisted Hair Regrowth and Microneedling for the Treatment of Alopecia Areata: A Review
Abstract
Alopecia areata (AA) affects approximately 2.1% of the population, with women being affected more often than men. Current therapies consisting of topical corticosteroids or intralesional injections are often the first choices for treatment, but are limited by unsatisfactory outcomes or risks to patients. Recently, fractional lasers and microneedling, with or without the addition of topical agents, have been examined as treatment options. A literature review was performed to evaluate the efficacy of fractional lasers in the treatment of AA. A total of six fractional lasers and two microneedling studies consisting of small prospective and retrospective studies, and case reports were reviewed. The number of trials and participants are limited, but evidence suggests that fractional lasers and microneedling may be effective therapeutic approaches when coupled with topical agents. Larger studies are required to better understand the effects of these treatment modalities for AA.
Keywords: alopecia areata; fractional lasers; hair loss; laser-assisted drug delivery; lasers; microneedling.
Conflict of interest statement
The authors have declared that no competing interests exist.
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References
-
- Guidelines for the management of alopecia areata. Hull SPM, Wood ML, Hutchinson PE, Sladden M, Messenger AG. Br J Dermatol. 2003;149:692–699. - PubMed
-
- Alopecia areata: a review of disease pathogenesis. Rajabi F, Drake LA, Senna MM, Rezaei N. Br J Dermatol. 2018;179:1033–1048. - PubMed
-
- Histopathology of alopecia: a clinicopathological approach to diagnosis. Stefanato CM. Histopathology. 2010;56:24–38. - PubMed
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