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Editorial
. 2019 Aug 27;34(4):I-IV.
doi: 10.21470/1678-9741-2019-0290.

Importance of Research in the Training of Thoracic Surgeons

Hartzell V Schaff  1 , Anita Nguyen  1
Affiliations
Editorial

Importance of Research in the Training of Thoracic Surgeons

Hartzell V Schaff et al. Braz J Cardiovasc Surg. .
No abstract available

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Figures

Fig. 1
Fig. 1
Experimental studies of ischemic arrest and reperfusion illustrate a mechanism of elevated end-diastolic pressure. End-diastolic pressure volume curves from a typical experiment in an isolated heart preparation demonstrate that prearrest and postarrest curves are exponential; postarrest diastolic pressure (Ped) is greater than prearrest diastolic pressure at any end-diastolic volume (Ved). As seen in the lower exponential plot, the end-diastolic pressure volume relationship is shifted upward and to the left and is not due to an increase in the slope or stiffness constant (α). Rather, the increased pressure is due to a reduction in the unstressed volume (β), i.e, a smaller cavity. Copyrighted and used with permission from the American Physiological Society[7].
Fig. 2
Fig. 2
Panel A shows preoperative magnetic resonance image and illustration of a patient with apical hypertrophic cardiomyopathy. Panel B shows enlargement of the left ventricular cavity following apical myectomy. Copyrighted and used with permission from Elsevier Inc[6].
Fig. 3
Fig. 3
Survival of patients who underwent apical myectomy at Mayo Clinic (blue) and hypertrophic cardiomyopathy patients on a national transplant waitlist (red). Copyrighted and used with permission from Elsevier Inc[6].
See this image and copyright information in PMC

References

    1. Schaff HV, Dombroff R, Flaherty JT, Bulkley BH, Hutchins GM, Goldman RA, et al. Effect of potassium cardioplegia on myocardial ischemia and post arrest ventricular function. Circulation. 1978;58(2):240–249. doi: 10.1161/01.cir.58.2.240. - DOI - PubMed
    1. Flaherty JT, Schaff HV, Goldman RA, Gott VL. Metabolic and functional effects of progressive degrees of hypothermia during global ischemia. Am J Physiol. 1979;236(6):H839–H845. doi: 10.1152/ajpheart.1979.236.6.H839. - DOI - PubMed
    1. Schaff HV, Goldman RA, Bulkley BH, Gott VL, Flaherty JT. Hyperosmolar reperfusion following ischemic cardiac arrest: critical importance of the timing of mannitol administration on preservation of myocardial structure and function. Surgery. 1981;89(2):141–150. - PubMed
    1. Binder J, Attenhofer Jost CH, Klarich KW, Connolly HM, Tajik AJ, Scott CG, et al. Apical hypertrophic cardiomyopathy: prevalence and correlates of apical outpouching. J Am Soc Echocardiogr. 2011;24(7):775–781. doi: 10.1016/j.echo.2011.03.002. - DOI - PubMed
    1. Schaff HV, Brown ML, Dearani JA, Abel MD, Ommen SR, Sorajja P, et al. Apical myectomy: a new surgical technique for management of severely symptomatic patients with apical hypertrophic cardiomyopathy. J Thorac Cardiovasc Surg. 2010;139(3):634–640. doi: 10.1016/j.jtcvs.2009.07.079. - DOI - PubMed

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