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. 2019 Aug 28;12(1):545.
doi: 10.1186/s13104-019-4593-5.

Weight management merits attention in women with infertility: a cross-sectional study on the association of anthropometric indices with hormonal imbalance in a Ghanaian population

William K B A Owiredu  1 , Peter Ntim Ofori  2 , Cornelius Archer Turpin  3 , Christian Obirikorang  1 , Emmanuel Acheampong  4 , Enoch Odame Anto  4 , Eddie-Williams Owiredu  1 , Evans Asamoah Adu  5
Affiliations

Weight management merits attention in women with infertility: a cross-sectional study on the association of anthropometric indices with hormonal imbalance in a Ghanaian population

William K B A Owiredu et al. BMC Res Notes. .

Abstract

Objective: This study determined the association of anthropometric indices with hormonal imbalance among infertile women in a Ghanaian population.

Results: Follicle stimulating hormone (FSH) levels (18.47 vs. 8.67, p-value = 0.002), and luteinizing hormone (LH) (12.43 vs. 8.01, p-value = 0.044) were higher in women with primary infertility compared with women presenting with secondary infertility. Waist circumference (WC) and waist-to-height ratio (WHtR) showed significant negative partial correlation with prolactin in both primary and secondary infertile women. Also a significant negative partial correlation was observed between BMI and prolactin in secondary infertile women only. Waist-to-hip ratio (WHR) showed a positive association with LH in both primary and secondary infertility. WHR also showed significant positive correlation to LH/FSH ratio in secondary infertility whereas body adiposity index (BAI) showed a negative correlation to LH/FSH ratio. In a correlation analysis of anthropometric measures with hormonal profile and causes of infertility as a fixed factor, the association between anthropometric indices and fertility hormones was largely dependent on the underlying causes of infertility.

Keywords: Anthropometric indices; Fertility hormones; Hormonal imbalance.

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Conflict of interest statement

The authors declare that they have no competing interests.

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