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Review
. 2019 Oct;37(4):505-517.
doi: 10.1016/j.det.2019.05.008. Epub 2019 Jul 10.

Kaposi Sarcoma Updates

Shervin A Etemad  1 , Anna K Dewan  2
Affiliations
Review

Kaposi Sarcoma Updates

Shervin A Etemad et al. Dermatol Clin. 2019 Oct.

Abstract

Kaposi sarcoma (KS) is an angioproliferative mesenchymal neoplasm caused by Kaposi sarcoma-related herpesvirus. This review outlines our current understanding of the epidemiology, pathogenesis, clinical presentation, and staging for this disease. Recent research has informed a more comprehensive understanding of the epidemiology of KS in the post-antiretroviral therapy era, and highlights the continued need to better characterize the African endemic subtype. Advances in clinical oncology, including checkpoint inhibitors and new skin-directed therapies, have translated into exciting new developments for the future of KS treatment options.

Keywords: AIDS; HHV8; HIV; Immunosuppression; Kaposi sarcoma; Sarcoma.

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