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Review
. 2019 Oct;30(4):433-444.
doi: 10.1016/j.nec.2019.05.004. Epub 2019 Jul 10.

Management of Giant Pituitary Adenomas: Role and Outcome of the Endoscopic Endonasal Surgical Approach

Miguel Marigil Sanchez  1 , Claire Karekezi  2 , Joao Paulo Almeida  3 , Aristotelis Kalyvas  3 , Vitor Castro  3 , Carlos Velasquez  4 , Fred Gentili  3
Affiliations
Review

Management of Giant Pituitary Adenomas: Role and Outcome of the Endoscopic Endonasal Surgical Approach

Miguel Marigil Sanchez et al. Neurosurg Clin N Am. 2019 Oct.

Abstract

Giant adenomas represent a significant surgical challenge. Although traditionally several transcranial and transsphenoidal microscopic approaches have had a central role in their management, in the last 2 decades here have been increasing reports of the endoscopic endonasal approach for giant adenomas, citing its improved resection rates and lower complication profile. However, its role as the preferred approach has not been fully established and there is currently a paucity of evidence-based recommendations available in the literature. This article reviews the current literature and attempts to define the role and outcomes of the endoscopic endonasal surgical approach for giant pituitary adenomas.

Keywords: Adenomas; Endoscopic; Giant; Pituitary; Transsphenoidal.

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