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Comment
. 2019 Oct;30(10):687-689.
doi: 10.1016/j.tem.2019.08.001. Epub 2019 Aug 28.

Lots of Movement in Gut and Parkinson's Research

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Lots of Movement in Gut and Parkinson's Research

Gabriela Mercado et al. Trends Endocrinol Metab. 2019 Oct.

Abstract

A new mouse model of Parkinson's disease (PD) demonstrates α-synuclein pathology spreading from the gut to the brain via the vagus nerve (Kim et al., Neuron, 2019). The pathology is associated with motor and non-motor behavioral deficits in wild-type mice. These findings support the idea that the gut could be a starting point for PD.

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