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. 1979:25:167-72.
doi: 10.1159/000402937.

On the mechanism of vestibular disturbances caused by industrial solvents

On the mechanism of vestibular disturbances caused by industrial solvents

L M Odkvist et al. Adv Otorhinolaryngol. 1979.

Abstract

The industrial solvents xylene, styrene, trichloroethylene and methylchloroform administered to rabbits caused a positional nystagmus and disturbances in the nystagmus response to rotatory acceleration. The positional nystagmus had a beat direction the opposite to positional alcohol nystagmus, which was in similar experiments elicited by methanol, ethanol and propanol. The three alcohols needed a ten times higher blood concentration to cause a nystagmus than the solvents did.

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