On the mechanism of vestibular disturbances caused by industrial solvents
- PMID: 314738
- DOI: 10.1159/000402937
On the mechanism of vestibular disturbances caused by industrial solvents
Abstract
The industrial solvents xylene, styrene, trichloroethylene and methylchloroform administered to rabbits caused a positional nystagmus and disturbances in the nystagmus response to rotatory acceleration. The positional nystagmus had a beat direction the opposite to positional alcohol nystagmus, which was in similar experiments elicited by methanol, ethanol and propanol. The three alcohols needed a ten times higher blood concentration to cause a nystagmus than the solvents did.
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