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Comment
. 2019 Sep;19(9):929-930.
doi: 10.1016/S1473-3099(19)30442-6.

Culture-negative cryptococcal meningitis

Kenneth Ssebambulidde  1 , Caleb Skipper  2 , Joshua Rhein  3
Affiliations
Comment

Culture-negative cryptococcal meningitis

Kenneth Ssebambulidde et al. Lancet Infect Dis. 2019 Sep.
No abstract available

PubMed Disclaimer

Conflict of interest statement

We declare no competing interests.

Figures

Figure 1:
Figure 1:. Kaplan-Meier analysis of survival for patients with cryptococcal meningitis stratified by CSF quantitative cryptococcal culture.
Probability of survival of patients with sterile CSF cultures (N=64), CSF quantitative cryptococcal culture of < 70,000 CFU/mL (N=319), and CSF quantitative cryptococcal culture ≥ 70,000 (N=320). The figure, which includes all participants in ASTRO-CM pilot and randomized trials (ClinicalTrials.gov, number NCT01802385), suggests a similar mortality in those presenting with sterile and higher initial fungal burdens. Diagnosis of cryptococcal meningitis was based on a positive CSF cryptococcal antigen. CSF=cerebrospinal fluid. QCC=quantitative cryptococcal culture.
See this image and copyright information in PMC

Comment on

References

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