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. 1988;144(11):701-3.

[Spinal mechanism of the antispastic action of TRH in patients with amyotrophic lateral sclerosis]

[Article in French]
C Morin  1 , E Pierrot-Deseilligny
Affiliations
  • PMID: 3148185

[Spinal mechanism of the antispastic action of TRH in patients with amyotrophic lateral sclerosis]

[Article in French]
C Morin et al. Rev Neurol (Paris). 1988.

Abstract

Effects of high-dose TRH on the vibratory inhibition of soleus H-reflex have been studied in 9 patients with amyotrophic lateral sclerosis. In 6 of the 9, TRH induced a significant increase in vibratory inhibition. This suggests that the TRH-induced reduction of spasticity might be due to an increase in presynaptic inhibition acting on Ia fibres.

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