Tumour serine proteases C1r and C1s as novel biomarkers and therapeutic targets in invasive sporadic and recessive dystrophic epidermolysis bullosa-associated cutaneous squamous cell carcinoma
- PMID: 31486079
- DOI: 10.1111/bjd.18419
Tumour serine proteases C1r and C1s as novel biomarkers and therapeutic targets in invasive sporadic and recessive dystrophic epidermolysis bullosa-associated cutaneous squamous cell carcinoma
Comment on
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Tumour-cell-derived complement components C1r and C1s promote growth of cutaneous squamous cell carcinoma.Br J Dermatol. 2020 Mar;182(3):658-670. doi: 10.1111/bjd.18095. Epub 2019 Jul 28. Br J Dermatol. 2020. PMID: 31049937 Free PMC article.
References
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- Riihilä P, Viiklepp K, Nissinen L et al. Tumour-cell-derived complement components C1r and C1s promote growth of cutaneous squamous cell carcinoma. Br J Dermatol 2020; 182:658-70.
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- Boyle S, Kopecki Z. Mechanical force and actin dynamics during cutaneous squamous cell carcinoma (cSCC) progression: opportunities for new treatment modalities. In: Squamous Cell Carcinoma - Hallmark and treatment modalities. London: IntechOpen Limited, (forthcoming); chapter available as open access online at: https://doi.org/10.5772/intechopen.86041
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- Fine JD, Bruckner-Tuderman L, Eady RA et al. Inherited epidermolysis bullosa: updated recommendations on diagnosis and classification. J Am Acad Dermatol 2014; 70:1103-26.
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- Murray AS, Varela FA, List K. Type II transmembrane serine proteases as potential targets for cancer therapy. Biol Chem 2016; 397:815-26.
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- Atanasova VS, Pourreyron C, Farshchian M et al. Identification of rigosertib for the treatment of recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma. Clin Cancer Res 2019; 25:3384-91.
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