Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Dec;49(12):5009-5022.
doi: 10.1007/s10803-019-04207-6.

Differences in the Late Positive Potential and P300 to Emotional Faces in Individuals with Autism Spectrum Disorder

Cara M Keifer  1 , Kathryn M Hauschild  2 , Brady D Nelson  2 , Greg Hajcak  3 , Matthew D Lerner  4
Affiliations

Differences in the Late Positive Potential and P300 to Emotional Faces in Individuals with Autism Spectrum Disorder

Cara M Keifer et al. J Autism Dev Disord. 2019 Dec.

Abstract

Despite evidence suggesting differences in early event-related potential (ERP) responses to social emotional stimuli, little is known about later stage ERP contributions to social emotional processing in individuals with autism spectrum disorder (ASD). Adults with and without ASD completed a facial emotion recognition task involving stimuli that varied by emotional intensity while electroencephalograms were recorded. Principal components analysis was used to examine P300 and late positive potential (LPP) modulation by emotional intensity. Results indicated that greater ASD symptomatology evinced heightened P300 to high relative to low intensity faces, then heightened LPP to low relative to high intensity faces. Findings suggest that adults with greater ASD symptomatology may demonstrate a lag in engagement in elaborative processing of low intensity faces.

Keywords: Autism spectrum disorder; ERP; Emotion processing; LPP; P300; Social cognition.

PubMed Disclaimer

References

    1. J Autism Dev Disord. 2001 Feb;31(1):37-45 - PubMed
    1. Dev Psychopathol. 2014 Nov;26(4 Pt 1):933-45 - PubMed
    1. Soc Cogn Affect Neurosci. 2012 Jun;7(5):578-87 - PubMed
    1. Pediatr Res. 2011 May;69(5 Pt 2):55R-62R - PubMed
    1. J Neural Transm (Vienna). 2014 Sep;121(9):1171-81 - PubMed