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Editorial
. 2019 Sep 5;15(9):e1007954.
doi: 10.1371/journal.ppat.1007954. eCollection 2019 Sep.

Promotion and induction of liver cancer by gut microbiome-mediated modulation of bile acids

Baolei Jia  1   2 , Che Ok Jeon  2
Affiliations
Editorial

Promotion and induction of liver cancer by gut microbiome-mediated modulation of bile acids

Baolei Jia et al. PLoS Pathog. .
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Schematic representation of the two pathways through which the gut microbiome putatively promotes liver cancer via antitumor immunosuppression.
BAs marked with an asterisk are from rats and mice only. BA, bile acid; CA, cholic acid; CDCA, chenodeoxycholic acid; COX2, cyclooxygenase 2; CXCL16, chemokine (C-X-C motif) ligand 16; CXCR6, C-X-C chemokine receptor type 6; DCA, deoxycholic acid; GLCA, glucuronic acid; HCA, hyocholic acid; HDCA, hyodeoxycholic acid; LCA, lithocholic acid; LTA, lipoteichoic acid; MCA, muricholic acid; MDCA, murideoxycholic acid; PGE2, prostaglandin E2; PTGER4, prostaglandin E receptor 4; UDCA, ursodeoxycholic acid.
See this image and copyright information in PMC

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