A Circuit Perspective on State-Dependent Effects of Dopamine Stimulants
- PMID: 31487524
- DOI: 10.1016/j.neuron.2019.08.022
A Circuit Perspective on State-Dependent Effects of Dopamine Stimulants
Abstract
Drugs often target multiple neuronal types. Thus, their behavioral effects may vary according to brain-state-dependent inter-neuronal interactions. In this issue of Neuron, Alhadeff et al. (2019) document hunger and dopamine-dependent alcohol effects, revealing specific circuit-level determinants of variable drug outcomes.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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Natural and Drug Rewards Engage Distinct Pathways that Converge on Coordinated Hypothalamic and Reward Circuits.Neuron. 2019 Sep 4;103(5):891-908.e6. doi: 10.1016/j.neuron.2019.05.050. Epub 2019 Jul 2. Neuron. 2019. PMID: 31277924 Free PMC article.
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