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. 2019 Sep 1;17(9):1109-1133.
doi: 10.6004/jnccn.2019.0043.

Small Bowel Adenocarcinoma, Version 1.2020, NCCN Clinical Practice Guidelines in Oncology

Al B Benson  1 , Alan P Venook  2 , Mahmoud M Al-Hawary  3 , Mustafa A Arain  2 , Yi-Jen Chen  4 , Kristen K Ciombor  5 , Stacey A Cohen  6 , Harry S Cooper  7 , Dustin A Deming  8 , Ignacio Garrido-Laguna  9 , Jean L Grem  10 , Sarah E Hoffe  11 , Joleen Hubbard  12 , Steven Hunt  13 , Ahmed Kamel  14 , Natalie Kirilcuk  15 , Smitha Krishnamurthi  16 , Wells A Messersmith  17 , Jeffrey Meyerhardt  18 , Eric D Miller  19 , Mary F Mulcahy  1 , Steven Nurkin  20 , Michael J Overman  21 , Aparna Parikh  22 , Hitendra Patel  23 , Katrina S Pedersen  13 , Leonard B Saltz  24 , Charles Schneider  25 , David Shibata  26 , John M Skibber  21 , Constantinos T Sofocleous  24 , Elena M Stoffel  3 , Eden Stotsky-Himelfarb  27 , Christopher G Willett  28 , Alyse Johnson-Chilla  29 , Kristina M Gregory  29 , Lisa A Gurski  29
Affiliations

Small Bowel Adenocarcinoma, Version 1.2020, NCCN Clinical Practice Guidelines in Oncology

Al B Benson et al. J Natl Compr Canc Netw. .

Abstract

Small bowel adenocarcinoma (SBA) is a rare malignancy of the gastrointestinal tract that has increased in incidence across recent years. Often diagnosed at an advanced stage, outcomes for SBA are worse on average than for other related malignancies, including colorectal cancer. Due to the rarity of this disease, few studies have been done to direct optimal treatment, although recent data have shown that SBA responds to treatment differently than colorectal cancer, necessitating a separate approach to treatment. The NCCN Guidelines for Small Bowel Adenocarcinoma were created to establish an evidence-based standard of care for patients with SBA. These guidelines provide recommendations on the workup of suspected SBA, primary treatment options, adjuvant treatment, surveillance, and systemic therapy for metastatic disease. Additionally, principles of imaging and endoscopy, pathologic review, surgery, radiation therapy, and survivorship are described.

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