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. 2019 Jun 6:33:91.
doi: 10.11604/pamj.2019.33.91.17000. eCollection 2019.

Intradialysis blood pressure changes among chronic kidney disease patients on maintenance haemodialysis in a tertiary hospital south - south Nigeria: a 2 year retrospective study

Henry Ohem Okpa  1   2 , Emmanuel Edet Effa  1   2 , Sidney Kelechi Oparah  2 , John Austin Chikezie  3   4 , Elvis Mbu Bisong  5 , Patrick Ntui Mbu  1 , Daniel Emmanuel Otokpa  1
Affiliations

Intradialysis blood pressure changes among chronic kidney disease patients on maintenance haemodialysis in a tertiary hospital south - south Nigeria: a 2 year retrospective study

Henry Ohem Okpa et al. Pan Afr Med J. .

Abstract

Introduction: Haemodialysis (HD) which is a form of renal replacement therapy commonly prescribed for patients with chronic kidney disease (CKD). However, it is not without deleterious haemodynamic responses which may occur either during or immediately after the termination of the procedure. These may include hypotension or hypertension.

Methods: This was a retrospective study that reviewed chronic kidney disease (CKD) patients on maintenance haemodialysis at the renal unit of University of Calabar Teaching Hospital, Calabar, Nigeria. In all, 71 patients were reviewed but only 64 patients had complete data for analysis. Socio-demographic, clinical and biochemical data were obtained from the records in the dialysis unit.

Results: There were more males 38 (59.4%) than females 26 (40.6%) in the study. The mean age was 51.71±15.43 years and 43.04±14.03years for males and females respectively. The prevalence of intradialysis hypertension 29 (45.3%) was higher than that of intradialysis hypotension 20 (31.3%) and the commonest cause of CKD requiring haemodialysis was diabetic nephropathy. The factors associated with intradialysis hypotension were lower post-dialysis systolic blood pressure (PDSBP), diastolic blood pressure (DBP), mean arterial pressure (MAP) and less number of antihypertensive medications; while the factors associated with intradialysis hypertension were higher post-dialysis systolic blood pressure (SBP), MAP, greater number of antihypertensive medications and longer duration of haemodialysis.

Conclusion: Our study shows that there are several modifiable factors associated with blood pressure fluctuations among CKD patients on maintenance haemodialysis in the renal unit of the University of Calabar Teaching Hospital, Calabar.

Keywords: Chronic kidney disease; haemodialysis; intradialysis hypertension; intradialysis hypotension.

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Conflict of interest statement

The authors declare no competing interests.

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References

    1. Assimon MM, Flythe JE. Intradialytic blood pressure abnormalities: the highs, the lows and all that lies between. Am J Nephrol. 2015;42(5):337–350. - PMC - PubMed
    1. Inrig JK. Intradialytic hypertension: a less-recognized cardiovascular complication of hemodialysis. Am J Kidney Dis. 2010;55(3):580–589. - PMC - PubMed
    1. Inrig JK, Oddone EZ, Hasselblad V, Barbara G, Patel UD, Reddan D, et al. Association of intradialytic blood pressure changes with hospitalization and mortality rates in prevalent ESRD patients. Kidney Int. 2007;71(5):454–461. - PMC - PubMed
    1. Levin NW. Intradialytic hypertension, I. Semin Dial. 1993;6:370–371.
    1. Fellner SK. Intradialytic hypertension, II. Semin Dial. 1993;6:371–373.

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