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Editorial
. 2019 Aug;8(4):404-406.
doi: 10.21037/hbsn.2019.03.20.

Bad neighborhoods: apoptotic and necroptotic microenvironments determine liver cancer subtypes

Dieter Adam  1
Affiliations
Editorial

Bad neighborhoods: apoptotic and necroptotic microenvironments determine liver cancer subtypes

Dieter Adam. Hepatobiliary Surg Nutr. 2019 Aug.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

Comment on

  • Necroptosis microenvironment directs lineage commitment in liver cancer.
    Seehawer M, Heinzmann F, D'Artista L, Harbig J, Roux PF, Hoenicke L, Dang H, Klotz S, Robinson L, Doré G, Rozenblum N, Kang TW, Chawla R, Buch T, Vucur M, Roth M, Zuber J, Luedde T, Sipos B, Longerich T, Heikenwälder M, Wang XW, Bischof O, Zender L. Seehawer M, et al. Nature. 2018 Oct;562(7725):69-75. doi: 10.1038/s41586-018-0519-y. Epub 2018 Sep 12. Nature. 2018. PMID: 30209397 Free PMC article.

References

    1. Philipp S, Sosna J, Adam D. Cancer and necroptosis: friend or foe? Cell Mol Life Sci 2016;73:2183-93. 10.1007/s00018-016-2193-2 - DOI - PMC - PubMed
    1. Conrad M, Angeli JP, Vandenabeele P, et al. Regulated necrosis: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 2016;15:348-66. 10.1038/nrd.2015.6 - DOI - PMC - PubMed
    1. Wang Y, Gao W, Shi X, et al. Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. Nature 2017;547:99-103. 10.1038/nature22393 - DOI - PubMed
    1. Galluzzi L, Vitale I, Aaronson SA, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death Differ 2018;25:486-541. 10.1038/s41418-017-0012-4 - DOI - PMC - PubMed
    1. Fuchslocher Chico J, Saggau C, Adam D. Proteolytic control of regulated necrosis. Biochim Biophys Acta Mol Cell Res 2017;1864:2147-61. 10.1016/j.bbamcr.2017.05.025 - DOI - PubMed