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. 1979 Sep 15;35(9):1230-2.
doi: 10.1007/BF01963307.

Peritoneal macrophages from adjuvant arthritic rats enhance tumour cell growth in vitro

L Binderup, E Bramm, E Arrigoni-Martelli

Peritoneal macrophages from adjuvant arthritic rats enhance tumour cell growth in vitro

L Binderup et al. Experientia. .

Abstract

Peritoneal macrophages from rats with adjuvant arthritis enhance the incorporation of 3H-thymidine in 2 tumour cell lines in vitro. Maximal enhancement is found during the development of the secondary lesions, and it is suggested that the immunologic commitment of the macrophages could interfere with their regulation of tumour cell proliferation in vivo.

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