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. 2019 Sep-Oct;23(5):313-321.
doi: 10.1016/j.bjid.2019.08.001. Epub 2019 Sep 3.

Validity and reliability of the 36-Item Short Form Health Survey questionnaire version 2 among people living with HIV in Brazil

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Validity and reliability of the 36-Item Short Form Health Survey questionnaire version 2 among people living with HIV in Brazil

Liliane Lins-Kusterer et al. Braz J Infect Dis. 2019 Sep-Oct.

Abstract

Background: The 36-Item Short Form Health Survey questionnaire (SF-36) is a widely used instrument for evaluating health-related quality-of-life (HRQoL). The psychometric validation of the SF-36 version 2.0 (SF-36v2) in HIV-infected patients had not yet conducted in Brazil.

Aim: To test data quality, reliability and validity of the SF-36v2 as a measure of HRQoL among Brazilian individuals living with HIV.

Methods: A cross-sectional study included 393 HIV-infected patients in whom HRQoL was assessed by using the SF-36v2 questionnaire. Demographic characteristics, socioeconomic status and clinical data were also collected. The SF-36 version 1 translated into Brazilian-Portuguese was adapted and introduced version 2 improvements according to the instrument developers. SPSS version 21 was used for data analyses. Confirmatory factor analysis (CFA) and structural equation modelling were performed using AMOS SPSS version 18. T-test for independent samples was used to compare differences between mean levels of HRQoL components in different groups. Linear multiple regression techniques were used to analyze the relationship between Physical Component Summary (PCS), Mental Component Summary (MCS) and independent variables.

Results: We performed the CFA and tested the hypothetical measurement model. We included five parameters to improve the adherence of data to the model. All indicators met the requirement suggested by specialized literature (χ2 (gl): 980.7 (527); CFI: 0.949; GFI: 0.873; TLI: 0.943; RMSEA: 0.047; 90% IC: 0.042-0.051). Multiple regression analyses revealed that depression (p=0.001), family income (p=0.007), sex (p=0.001) and age (p<0.021) were associated with MCS. Comorbidities (p=0.001), health self-perception (p=0.001), age (p=0.001), and sex (p=0.025) were associated with PCS.

Conclusions: A consistent validation of the SF-36v2 in Brazilian HIV patients were shown. Further studies with SF-36v2 psychometric analyses would be required in other populations to establish Brazilian normative data.

Keywords: HIV; factor analysis; health-related quality of life; validation studies..

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Figures

Figure 1
Figure 1
The measurement model for CFA combining all eight domains of SF-36v2 with standardized factor loads and correlation coefficients between factors.
Figure 2
Figure 2
SF-36v2 final structural model, with standardized factor loads and correlation coefficients between Summaries Components.

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References

    1. Deeks S.G., Lewin S.R., Havlir D.V. The End of AIDS: HIV Infection as a Chronic Disease. Lancet. 2013;382:1525–1533. - PMC - PubMed
    1. Betancur M.N., Lins L., Oliveira I.R., Brites C. Quality of life, anxiety and depression in patients with HIV/AIDS who present poor adherence to antiretroviral therapy: a cross-sectional study in Salvador, Brazil. Braz J Infect Dis. 2017;21:507–514. - PMC - PubMed
    1. Lédo A.P., Rodriguez-Prieto I., Lins L., Neto M.G., Brites C. Association Between Health-Related Quality of Life and Physical Functioning in Antiretroviral-Naive HIV-Infected Patients. Open AIDS J. 2018;12:117–125. - PMC - PubMed
    1. Clayson D.J., Wild D.J., Quarterman P., Duprat-Lomon I., Kubin M., Coons S.J.A. A comparative review of health-related quality-of-life measures for use in HIV/AIDS clinical trials. PharmacoEconomics. 2006;24:751–765. - PubMed
    1. Lins L., Carvalho F.M. SF-36 total score as a single measure of health-related quality of life: Scoping review. SAGE Open Med. 2016;4:1–12. - PMC - PubMed

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