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Comment
. 2019 Sep 5;25(3):299-300.
doi: 10.1016/j.stem.2019.08.006.

Changing the Rules of the Game: How Winners Become Losers during Oncogenic Cell Selection

Cristina Villa Del Campo  1 , Miguel Torres  2
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Changing the Rules of the Game: How Winners Become Losers during Oncogenic Cell Selection

Cristina Villa Del Campo et al. Cell Stem Cell. .
Free article

Abstract

As we age, our tissues become a mosaic of random mutations, many of which are oncogenic and promote the expansion of their carrier cells. In this issue of Cell Stem Cell, Fernandez-Antoran et al. (2019) show how commonly used medical procedures modify cell selection dynamics to either expand or eliminate cells carrying oncogenic p53 mutations.

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