Aging of the Hematopoietic Stem Cell Niche: An Unnerving Matter
- PMID: 31491392
- DOI: 10.1016/j.stem.2019.08.008
Aging of the Hematopoietic Stem Cell Niche: An Unnerving Matter
Abstract
The drivers of aging in the hematopoietic system remain incompletely understood. In this issue of Cell Stem Cell, Ho et al. (2019) report that functional switching of β-adrenergic nerve signaling underlies remodeling of stem cell niches, driving age-associated alterations in hematopoiesis.
Copyright © 2019 Elsevier Inc. All rights reserved.
Comment on
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Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging.Cell Stem Cell. 2019 Sep 5;25(3):407-418.e6. doi: 10.1016/j.stem.2019.06.007. Epub 2019 Jul 11. Cell Stem Cell. 2019. PMID: 31303548 Free PMC article.
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