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Comment
. 2019 Sep 5;25(3):301-303.
doi: 10.1016/j.stem.2019.08.008.

Aging of the Hematopoietic Stem Cell Niche: An Unnerving Matter

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Aging of the Hematopoietic Stem Cell Niche: An Unnerving Matter

Marc H G P Raaijmakers. Cell Stem Cell. .
Free article

Abstract

The drivers of aging in the hematopoietic system remain incompletely understood. In this issue of Cell Stem Cell, Ho et al. (2019) report that functional switching of β-adrenergic nerve signaling underlies remodeling of stem cell niches, driving age-associated alterations in hematopoiesis.

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