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. 2021 Jan;38(2):182-190.
doi: 10.1055/s-0039-1696640. Epub 2019 Sep 6.

Gestational Weight Gain and Pregnancy Outcomes among Nulliparous Women

Annie M Dude  1 , William Grobman  1 , David Haas  2 , Brian M Mercer  3 , Samuel Parry  4 , Robert M Silver  5 , Ronald Wapner  6 , Deborah Wing  7 , George Saade  8 , Uma Reddy  9 , Jay Iams  10 , Michelle A Kominiarek  1
Affiliations

Gestational Weight Gain and Pregnancy Outcomes among Nulliparous Women

Annie M Dude et al. Am J Perinatol. 2021 Jan.

Abstract

Objective: To determine the association between total gestational weight gain and perinatal outcomes.

Study design: Data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be (NuMoM2b) study were used. Total gestational weight gain was categorized as inadequate, adequate, or excessive based on the 2009 Institute of Medicine guidelines. Outcomes examined included hypertensive disorders of pregnancy, mode of delivery, shoulder dystocia, large for gestational age or small for-gestational age birth weight, and neonatal intensive care unit admission.

Results: Among 8,628 women, 1,666 (19.3%) had inadequate, 2,945 (34.1%) had adequate, and 4,017 (46.6%) had excessive gestational weight gain. Excessive gestational weight gain was associated with higher odds of hypertensive disorders (adjusted odds ratio [aOR] = 2.05, 95% confidence interval [CI]: 1.78-2.36) Cesarean delivery (aOR = 1.24, 95% CI: 1.09-1.41), and large for gestational age birth weight (aOR = 1.49, 95% CI: 1.23-1.80), but lower odds of small for gestational age birth weight (aOR = 0.59, 95% CI: 0.50-0.71). Conversely, inadequate gestational weight gain was associated with lower odds of hypertensive disorders (aOR = 0.75, 95% CI: 0.62-0.92), Cesarean delivery (aOR = 0.77, 95% CI: 0.65-0.92), and a large for gestational age birth weight (aOR = 0.72, 95% CI: 0.55-0.94), but higher odds of having a small for gestational age birth weight (aOR = 1.64, 95% CI: 1.37-1.96).

Conclusion: Both excessive and inadequate gestational weight gain are associated with adverse maternal and neonatal outcomes.

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Conflict of interest statement

B.M.M. reports grants from NICHD, during the conduct of the study. R.W. received consulting fees from Natera, Bioreference, and Illumina, Inc, in addition to grants (that go directly to Columbia University) from Sequenom and Illumina, Inc., outside the submitted work.

Figures

Fig. 1
Fig. 1
Study sample. NuMoM2b, Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be study.
See this image and copyright information in PMC

References

    1. Harvey MW, Braun B, Ertel KA, Pekow PS, Markenson G, Chasan-Taber L. prepregnancy body mass index, gestational weight gain, and odds of cesarean delivery in hispanic women. Obesity (Silver Spring) 2018;26(01):185–192 - PMC - PubMed
    1. Hedderson MM, Gunderson EP, Ferrara A. Gestational weight gain and risk of gestational diabetes mellitus. Obstet Gynecol 2010; 115 (03):597–604 - PMC - PubMed
    1. Masho SW, Urban P, Cha S, Ramus R. Body mass index, weight gain, and hypertensive disorders in pregnancy. Am J Hypertens 2016;29(06):763–771 - PubMed
    1. Simas TA, Waring ME, Liao X, et al. Prepregnancy weight, gestational weight gain, and risk of growth affected neonates. JWomens Health (Larchmt) 2012;21(04):410–417 - PubMed
    1. Goldstein RF, Abell SK, Ranasinha S, et al. Gestational weight gain across continents and ethnicity: systematic review and meta-analysis of maternal and infant outcomes in more than one million women. BMC Med 2018;16(01):153. - PMC - PubMed

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