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Clinical Trial
. 1988:11 Suppl 2:S187-90.
doi: 10.1097/00000421-198801102-00043.

Total androgen blockade for metastatic cancer of the prostate

Affiliations
Clinical Trial

Total androgen blockade for metastatic cancer of the prostate

G Béland et al. Am J Clin Oncol. 1988.

Abstract

This randomized, double-blind study comparing orchiectomy plus placebo to orchiectomy plus a nonsteroid antiandrogen (Anandron) shows that total androgen blockade for metastatic cancer of the prostate provides a significantly better early objective response when compared to castration alone. This response, however, is less apparent at 18 months. The study also suggests a longer survival for the patients with total androgen blockade.

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