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Review
. 2019 Sep 7;21(10):126.
doi: 10.1007/s11886-019-1211-z.

Is There a Safety Concern for Drug-Coated Balloons in Peripheral Arterial Disease?

Mohamed M Gad  1   2 , Antonette K Karrthik  1 , Ahmad A Mahmoud  3 , Ahmed N Mahmoud  4
Affiliations
Review

Is There a Safety Concern for Drug-Coated Balloons in Peripheral Arterial Disease?

Mohamed M Gad et al. Curr Cardiol Rep. .

Abstract

Purpose of review: Drug-coated balloons (DEB) and drug-eluting stents (DES) emerged as a tool to aid in lowering the rates of neointimal hyperplasia and target lesion restenosis following endovascular peripheral arterial disease (PAD) interventions.

Recent findings: Although the initial trials comparing these devices with non-drug balloons and stents showed favorable results, more recent data raised concerns regarding the mid to long-term safety of these devices. In this review, we will discuss the evolution of endovascular therapy for PAD, with highlights regarding the recent debates on the long-term safety of the drug-coated devices for treatment of PAD.

Keywords: Endovascular therapy; Mortality; Paclitaxel; Peripheral arterial disease.

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