Osteoarticular infections: a specific program for older patients?

doi:10.1007/s40520-019-01329-w

Review

. 2021 Mar;33(3):703-710.

doi: 10.1007/s40520-019-01329-w. Epub 2019 Sep 7.

Osteoarticular infections: a specific program for older patients?

Ilker Uçkay^{1

2}, Dominique Holy³, Michael Betz⁴, Regina Sauer⁵, Tanja Huber⁶, Jan Burkhard^{7

3}

Affiliations

¹ Infectiology, Balgrist University Hospital, Forchstrasse 340, 8008, Zurich, Switzerland. ilker.uckay@balgrist.ch.
² Infection Control, Balgrist University Hospital, Zurich, Switzerland. ilker.uckay@balgrist.ch.
³ Internal Medicine, Balgrist University Hospital, Zurich, Switzerland.
⁴ Orthopaedic Surgery, Balgrist University Hospital, Zurich, Switzerland.
⁵ Nursing Care, Balgrist University Hospital, Zurich, Switzerland.
⁶ Pharmacy, Balgrist University Hospital, Zurich, Switzerland.
⁷ Infection Control, Balgrist University Hospital, Zurich, Switzerland.

PMID: 31494913
DOI: 10.1007/s40520-019-01329-w

Review

Osteoarticular infections: a specific program for older patients?

Ilker Uçkay et al. Aging Clin Exp Res. 2021 Mar.

. 2021 Mar;33(3):703-710.

doi: 10.1007/s40520-019-01329-w. Epub 2019 Sep 7.

Authors

Ilker Uçkay^{1

2}, Dominique Holy³, Michael Betz⁴, Regina Sauer⁵, Tanja Huber⁶, Jan Burkhard^{7

3}

Affiliations

¹ Infectiology, Balgrist University Hospital, Forchstrasse 340, 8008, Zurich, Switzerland. ilker.uckay@balgrist.ch.
² Infection Control, Balgrist University Hospital, Zurich, Switzerland. ilker.uckay@balgrist.ch.
³ Internal Medicine, Balgrist University Hospital, Zurich, Switzerland.
⁴ Orthopaedic Surgery, Balgrist University Hospital, Zurich, Switzerland.
⁵ Nursing Care, Balgrist University Hospital, Zurich, Switzerland.
⁶ Pharmacy, Balgrist University Hospital, Zurich, Switzerland.
⁷ Infection Control, Balgrist University Hospital, Zurich, Switzerland.

PMID: 31494913
DOI: 10.1007/s40520-019-01329-w

Abstract

Background: With the increasing number of elderly patients, arthroplasties, fractures and diabetic foot infections, the worldwide number of osteoarticular infections (OAI) among the elderly is concomitantly expected to rise.

Aims: We explore existing scientific knowledge about OAI in the frail elderly population.

Methods: We performed a literature search linking OAIs to geriatric patients and comparing elderly patients (> 65 years) with average adults (range 18-65 years).

Results: In this literature, financial aspects, comparison of diverse therapies on quality of life, reimbursement policies, or specific guidelines or nursing recommendations are missing. Age itself was not an independent factor related to particular pathogens, prevention of OAI, nursing care, and outcomes of OAI. However, geriatric patients were significantly more exposed to adverse events of therapy. They had more co-morbidities and more conservative surgery for OAI.

Conclusion: Available literature regarding OAI management among elderly patients is sparse. In recent evaluations, age itself does not seem an independent factor related to particular epidemiology, pathogens, prevention, nursing care, rehabilitation and therapeutic outcomes of OAI. Future clinical research will concern more conservative surgical indications, but certainly reduce inappropriate antibiotic use.

Keywords: Elderly; Epidemiology; Osteoarticular infections; Prevention; Therapy.

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References

1. Al-Mayahi M, Betz M, Muller DA et al (2013) Remission rate of implant-related infections following revision surgery after fractures. Int Orthop 37:2253–2258 - PubMed - PMC
1. Uçkay I, Aragon-Sanchez J, Lew D et al (2015) Diabetic foot infections: what have we learned in the last 30 years? Int J Infect Dis 40:81–91 - PubMed
1. Murillo O, Grau I, Lora-Tamayo J et al (2015) The changing epidemiology of bacteraemic osteoarticular infections in the early 21st century. Clin Microbiol Infect 21:254–262 - PubMed
1. Post V, Wahl P, Uçkay I et al (2014) Phenotypic and genotypic characterisation of Staphylococcus aureus causing musculoskeletal infections. Int J Med Microbiol 304:565–576 - PubMed
1. Tumminello A, Dominguez D, Lebowitz D et al (2017) Staphylococcus aureus versus streptococci in orthopaedic infections. Infect Dis (Lond) 49:716–718

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[1] Al-Mayahi M, Betz M, Muller DA et al (2013) Remission rate of implant-related infections following revision surgery after fractures. Int Orthop 37:2253–2258 - PubMed - PMC

[2] Al-Mayahi M, Betz M, Muller DA et al (2013) Remission rate of implant-related infections following revision surgery after fractures. Int Orthop 37:2253–2258 - PubMed - PMC

[3] Uçkay I, Aragon-Sanchez J, Lew D et al (2015) Diabetic foot infections: what have we learned in the last 30 years? Int J Infect Dis 40:81–91 - PubMed

[4] Uçkay I, Aragon-Sanchez J, Lew D et al (2015) Diabetic foot infections: what have we learned in the last 30 years? Int J Infect Dis 40:81–91 - PubMed

[5] Murillo O, Grau I, Lora-Tamayo J et al (2015) The changing epidemiology of bacteraemic osteoarticular infections in the early 21st century. Clin Microbiol Infect 21:254–262 - PubMed

[6] Murillo O, Grau I, Lora-Tamayo J et al (2015) The changing epidemiology of bacteraemic osteoarticular infections in the early 21st century. Clin Microbiol Infect 21:254–262 - PubMed

[7] Post V, Wahl P, Uçkay I et al (2014) Phenotypic and genotypic characterisation of Staphylococcus aureus causing musculoskeletal infections. Int J Med Microbiol 304:565–576 - PubMed

[8] Post V, Wahl P, Uçkay I et al (2014) Phenotypic and genotypic characterisation of Staphylococcus aureus causing musculoskeletal infections. Int J Med Microbiol 304:565–576 - PubMed

[9] Tumminello A, Dominguez D, Lebowitz D et al (2017) Staphylococcus aureus versus streptococci in orthopaedic infections. Infect Dis (Lond) 49:716–718

[10] Tumminello A, Dominguez D, Lebowitz D et al (2017) Staphylococcus aureus versus streptococci in orthopaedic infections. Infect Dis (Lond) 49:716–718

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Osteoarticular infections: a specific program for older patients?

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Osteoarticular infections: a specific program for older patients?

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