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Review
. 2019 Nov;32(6):e13084.
doi: 10.1111/dth.13084. Epub 2019 Oct 7.

The efficacy of fractional ablative carbon dioxide laser combined with other therapies in acne scars

Yun-Zhu Mu  1 , Lu Jiang  1 , Hao Yang  1
Affiliations
Review

The efficacy of fractional ablative carbon dioxide laser combined with other therapies in acne scars

Yun-Zhu Mu et al. Dermatol Ther. 2019 Nov.

Abstract

Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO2 laser with a wavelength of 10,600 nm is commonly used in the field of cosmetology and clinical therapies for various skin diseases, and it can effectively improve skin regeneration and scar formation. To obtain satisfactory results for patients with scars, repetitive fractional laser therapy is always required; however, this treatment could easily lead to complications such as erythema, edema, infection, and post-inflammatory hyperpigmentation. In addition, different types of acne scars may have different responses to laser, further limiting its widespread use. In recent studies both home and abroad, a new pattern of fractional laser combined with other therapies to improve acne scar has been recommended to guarantee the safety and effective of treatment. This article reviews the recent pertinent literatures and summarized the progression of ablative fractional CO2 laser combined with other therapies on acne scar.

Keywords: acne scars; combination therapy; fractional CO2 laser.

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References

REFERENCES

    1. Abdel, A. A., Ibrahim, I. M., Sami, N. A., & Abdel Kareem, I. M. (2018). Evaluation of autologous platelet rich plasma plus ablative carbon dioxide fractional laser in the treatment of acne scars. Journal of Cosmetic & Laser Therapy, 20(2), 106-113.
    1. Abdul-Aziz, I. A. I. T., Abdul-Aziz, A. S. A. R., Ahmed, M. H., & Kamal, A. M. (2019). Comparative study of the efficacy of platelet-rich plasma combined with carboxytherapy vs its use with fractional carbon dioxide laser in atrophic acne scars. Journal of Cosmetic Dermatology, 18, 150-155.
    1. Alexiades-Armenakas, M. R., Dover, J. S., & Arndt, K. A. (2008). The spectrum of laser skin resurfacing: Nonablative, fractional and ablative resurfacing. Journal of the American Academy of Dermatology, 58(5), 719-737.
    1. Anupama, Y. G., & Wahab, A. J. (2016). Effectiveness of CO2 laser with subcision in patients with acne scars. Journal of Cutaneous Laser Therapy, 18(7), 367-371.
    1. Banzhaf, C. A., Thaysen-Petersen, D., Bay, C., Philipsen, P. A., Mogensen, M., Prow, T., & Haedersdal, M. (2017). Fractional laser-assisted drug uptake: Impact of time-related topical application to achieve enhanced delivery. Lasers in Surgery & Medicine, 49(4), 348-354.