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Review
. 2019 Sep 4;15(661):1566-1571.

[Beta-blockers : myths and facts]

[Article in French]
Affiliations
  • PMID: 31496190
Review

[Beta-blockers : myths and facts]

[Article in French]
Pauline Gay Des Combes Gliven et al. Rev Med Suisse. .

Abstract

Beta-blockers are very commonly drugs used in clinical practice, but whose mechanisms and clinical impacts are not always well understood, especially in certain specific clinical situations. This article proposes a review of some pharmacology notions over the different generations of β-blockers, as well as a review of indications and side effects in particular clinical situations, such as COPD, portal hypertension with esophageal varices and erectile dysfunction. Finally, an overview of response variability of these treatments is discussed from a genetic point of view.

Les bêtabloquants sont des traitements médicamenteux couramment utilisés en pratique clinique mais dont les mécanismes et les impacts demeurent parfois méconnus, notamment dans certaines situations cliniques spécifiques. Cet article propose une revue de quelques notions pharmacologiques des différentes générations de bêtabloquants, ainsi que les indications et effets secondaires dans des situations cliniques particulières, comme la BPCO, l’hypertension portale avec varices œsophagiennes et la dysfonction érectile. Enfin, un survol de la variabilité de réponses à ces traitements est abordé notamment d’un point de vue génétique.

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Conflict of interest statement

Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.

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