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Review
. 2019 Jul-Sep;14(3):648-656.
doi: 10.4103/ajns.AJNS_14_19.

Current Updates on Idiopathic Normal Pressure Hydrocephalus

Affiliations
Review

Current Updates on Idiopathic Normal Pressure Hydrocephalus

Boon Seng Liew et al. Asian J Neurosurg. 2019 Jul-Sep.

Abstract

Idiopathic normal pressure hydrocephalus (iNPH) is one of the neurodegenerative diseases which can be treated surgically with favorable outcome. The gait disturbance, cognitive, and urinary symptoms are known as the clinical triad of iNPH. In this review, we have addressed the comorbidities, differential diagnoses, clinical presentations, and pathology of iNPH. We have also summarized the imaging studies and clinical procedures used for the diagnosis of iNPH. The treatment modality, outcomes, and prognosis were also discussed.

Keywords: Diagnostic methods; idiopathic normal pressure hydrocephalus; neuro-degenerative disease; surgical management.

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Conflict of interest statement

There are no conflicts of interest.

References

    1. Allali G, Laidet M, Armand S, Momjian S, Marques B, Saj A, et al. A combined cognitive and gait quantification to identify normal pressure hydrocephalus from its mimics: The Geneva's protocol. Clin Neurol Neurosurg. 2017;160:5–11. - PubMed
    1. Kuriyama N, Miyajima M, Nakajima M, Kurosawa M, Fukushima W, Watanabe Y, et al. Nationwide hospital-based survey of idiopathic normal pressure hydrocephalus in Japan: Epidemiological and clinical characteristics. Brain Behav. 2017;7:e00635. - PMC - PubMed
    1. Pyykkö OT, Nerg O, Niskasaari HM, Niskasaari T, Koivisto AM, Hiltunen M, et al. Incidence, comorbidities, and mortality in idiopathic normal pressure hydrocephalus. World Neurosurg. 2018;112:e624–31. - PubMed
    1. Israelsson H, Carlberg B, Wikkelsö C, Laurell K, Kahlon B, Leijon G, et al. Vascular risk factors in INPH: A prospective case-control study (the INPH-CRasH study) Neurology. 2017;88:577–85. - PMC - PubMed
    1. Andrén K, Wikkelsö C, Sundström N, Agerskov S, Israelsson H, Laurell K, et al. Long-term effects of complications and vascular comorbidity in idiopathic normal pressure hydrocephalus: A quality registry study. J Neurol. 2018;265:178–86. - PMC - PubMed