Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Jun 27;11(6):e5020.
doi: 10.7759/cureus.5020.

Radiation Recall in a Patient with Intrahepatic Cholangiocarcinoma: Case Report and a Literature Review

Affiliations
Case Reports

Radiation Recall in a Patient with Intrahepatic Cholangiocarcinoma: Case Report and a Literature Review

Waled Bahaj et al. Cureus. .

Abstract

Radiation recall dermatitis (RRD) is a rare and poorly understood phenomenon, constituting an inflammatory skin reaction to a previously irradiated area of skin following the administration of certain agents, usually chemotherapy. Our patient developed RRD 66 years after receiving radiation therapy; to the best of our knowledge, this is the longest reported period in the literature. The mainstay of therapy is to withhold the agent that elicited the adverse reaction, followed by symptomatic management. Subjecting patients to further chemotherapy can provoke another episode of RRD. Therefore, clinical judgment in this regard is usually recommended.

Keywords: gallbladder cancer; rash; recall dermatitis.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. MRI abdomen showing enhancing mass with necrotic center
Figure 2
Figure 2. Radiation recall dermatitis in the patient’s right arm and shoulder, extending to the anterior chest wall.

References

    1. Radiation recall: a well recognized but neglected phenomenon. Azria D, Magné N, Zouhair A, et al. Cancer Treat Rev. 2005;31:555–570. - PubMed
    1. Characterizing the phenomenon of radiation recall dermatitis. Camidge R, Price A. Radiother Oncol. 2001;59:237–245. - PubMed
    1. Radiation reaction recall following simvastatin therapy: a new observation. Abadir R, Liebmann J. Clin Oncol (R Coll Radiol) 1995;7:325–326. - PubMed
    1. Radiation recall in a patient with breast cancer treated for tuberculosis. Extermann M, Vogt N, Forni M, Dayer P. https://www.ncbi.nlm.nih.gov/pubmed/7621852. Eur J Clin Pharmacol. 1995;48:77–78. - PubMed
    1. Radiation recall associated with vinblastine in a patient treated for Kaposi sarcoma related to acquired immune deficiency syndrome. Nemechek PM, Corder MC. http://10.1002/1097-0142(19920915)70:6<1605::aid-cncr2820700627>3.0.co;2-s. Cancer. 1992;70:1605–1606. - PubMed

Publication types

LinkOut - more resources