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Case Reports
. 2018 Nov 30;34(2):225-228.
doi: 10.5606/ArchRheumatol.2019.7020. eCollection 2019 Jun.

Accelerated Nodulosis in a Patient With Rheumatoid Arthritis

Ayşe Ünal Enginar  1 , Hakan Nur  1 , Erdal Gilgil  2 , Cahit Kaçar  1
Affiliations
Case Reports

Accelerated Nodulosis in a Patient With Rheumatoid Arthritis

Ayşe Ünal Enginar et al. Arch Rheumatol. .

Abstract

In patients with rheumatoid arthritis (RA), subcutaneous nodules are the most frequently seen extra-articular findings that are seen in areas of extensor pressure. In this article, we present the case of a RA patient with accelerated nodulosis that started with the use of methotrexate and exacerbated with etanercept and leflunomide treatment.

Keywords: Accelerated nodulosis; anti-tumor necrosis factor drugs; methotrexate; rheumatoid arthritis.

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Conflict of interest statement

Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Figures

Figure 1
Figure 1. Nodulosis after etanercept. (a) hand, (b) foot
Figure 2
Figure 2. Biopsy in rheumatoid nodule (H-E¥50).
Figure 3
Figure 3. Nodulosis before leflunomide.
Figure 4
Figure 4. Nodulosis after termination of drugs.
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