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. 1988 Dec;32(12):1893-5.
doi: 10.1128/AAC.32.12.1893.

Heterogeneity of class I beta-lactamase expression in clinical isolates of Pseudomonas aeruginosa

C C Sanders  1 , M L Gates, W E Sanders Jr
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Heterogeneity of class I beta-lactamase expression in clinical isolates of Pseudomonas aeruginosa

C C Sanders et al. Antimicrob Agents Chemother. 1988 Dec.

Abstract

Expression of chromosomal beta-lactamase was examined in 85 clinical isolates of Pseudomonas aeruginosa. beta-Lactamase assays with and without cefoxitin induction revealed four phenotypes of enzyme expression: low basal, inducible; moderate basal, inducible; moderate basal, constitutive; and high basal, constitutive. The isoelectric points of the major beta-lactamase bands were 9.4, 9.2, and 8.4. These results indicate that there is a limited heterogeneity in expression of chromosomal beta-lactamase of P. aeruginosa.

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