Practice Guideline

. 2019 Oct 1;104(10):4660-4666.

doi: 10.1210/jc.2019-01603.

Global Consensus Position Statement on the Use of Testosterone Therapy for Women

Susan R Davis^{1

2}, Rodney Baber^{3

2

4}, Nicholas Panay^{5

2}, Johannes Bitzer^{6

7}, Sonia Cerdas Perez^{8

9}, Rakibul M Islam^{1

2}, Andrew M Kaunitz^{10

11}, Sheryl A Kingsberg^{12

13}, Irene Lambrinoudaki^{14

15}, James Liu^{16

11}, Sharon J Parish^{17

18}, JoAnn Pinkerton^{19

13}, Janice Rymer^{20

21}, James A Simon^{22

23

18}, Linda Vignozzi^{24

25

7}, Margaret E Wierman^{26

27}

Affiliations

¹ Women's Health Research Program, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
² The International Menopause Society.
³ University of Sydney, Sydney, Australia.
⁴ Royal Australian and New Zealand College of Obstetricians and Gynaecologists.
⁵ Queen Charlotte's & Chelsea and Westminster Hospitals and Imperial College, London, United Kingdom.
⁶ University Hospital Basel, Basel, Switzerland.
⁷ The International Society for Sexual Medicine.
⁸ Endocrinology Department, Hospital Cima and University of Costa Rica, San Jose, Costa Rica.
⁹ The Federacion Latinoamericana de Sociedades de Climaterio y Menopausia.
¹⁰ Department of Obstetrics and Gynecology, University of Florida College of Medicine, Jacksonville, Florida.
¹¹ The American College of Obstetricians and Gynecologists.
¹² Behavioral Medicine, University Hospitals Cleveland Medical Center and Case Western Reserve University School of Medicine, Cleveland, Ohio.
¹³ The North American Menopause Society.
¹⁴ Medical School, National and Kapodistrian University of Athens, Athens, Greece.
¹⁵ The European Menopause and Andropause Society.
¹⁶ Department of Obstetrics and Gynecology, University Hospitals Cleveland and Case Western Reserve University School of Medicine, Cleveland, Ohio.
¹⁷ Weill Cornell Medical College, New York, New York.
¹⁸ The International Society for the Study of Women's Sexual Health.
¹⁹ Department of Obstetrics and Gynecology, the University of Virginia Health System, Charlottesville, Virginia.
²⁰ King's College London, Guy's and St. Thomas' Foundation Hospital Trust, London, United Kingdom.
²¹ The Royal College of Obstetricians and Gynaecologists.
²² George Washington University, Washington, DC.
²³ IntimMedicine Specialists, Washington, DC.
²⁴ Department of Biomedical, Experimental and Clinical Sciences "Mario Serio," University of Florence, Florence, Italy.
²⁵ Careggi Hospital, Florence, Italy.
²⁶ Department of Medicine, Integrative Physiology and Obstetrics and Gynecology, University of Colorado, Anschutz Medical Campus, Colorado.
²⁷ The Endocrine Society.

PMID: 31498871
PMCID: PMC6821450
DOI: 10.1210/jc.2019-01603

Practice Guideline

Global Consensus Position Statement on the Use of Testosterone Therapy for Women

Susan R Davis et al. J Clin Endocrinol Metab. 2019.

. 2019 Oct 1;104(10):4660-4666.

doi: 10.1210/jc.2019-01603.

Authors

Affiliations

¹ Women's Health Research Program, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
² The International Menopause Society.
³ University of Sydney, Sydney, Australia.
⁴ Royal Australian and New Zealand College of Obstetricians and Gynaecologists.
⁵ Queen Charlotte's & Chelsea and Westminster Hospitals and Imperial College, London, United Kingdom.
⁶ University Hospital Basel, Basel, Switzerland.
⁷ The International Society for Sexual Medicine.
⁸ Endocrinology Department, Hospital Cima and University of Costa Rica, San Jose, Costa Rica.
⁹ The Federacion Latinoamericana de Sociedades de Climaterio y Menopausia.
¹⁰ Department of Obstetrics and Gynecology, University of Florida College of Medicine, Jacksonville, Florida.
¹¹ The American College of Obstetricians and Gynecologists.
¹² Behavioral Medicine, University Hospitals Cleveland Medical Center and Case Western Reserve University School of Medicine, Cleveland, Ohio.
¹³ The North American Menopause Society.
¹⁴ Medical School, National and Kapodistrian University of Athens, Athens, Greece.
¹⁵ The European Menopause and Andropause Society.
¹⁶ Department of Obstetrics and Gynecology, University Hospitals Cleveland and Case Western Reserve University School of Medicine, Cleveland, Ohio.
¹⁷ Weill Cornell Medical College, New York, New York.
¹⁸ The International Society for the Study of Women's Sexual Health.
¹⁹ Department of Obstetrics and Gynecology, the University of Virginia Health System, Charlottesville, Virginia.
²⁰ King's College London, Guy's and St. Thomas' Foundation Hospital Trust, London, United Kingdom.
²¹ The Royal College of Obstetricians and Gynaecologists.
²² George Washington University, Washington, DC.
²³ IntimMedicine Specialists, Washington, DC.
²⁴ Department of Biomedical, Experimental and Clinical Sciences "Mario Serio," University of Florence, Florence, Italy.
²⁵ Careggi Hospital, Florence, Italy.
²⁶ Department of Medicine, Integrative Physiology and Obstetrics and Gynecology, University of Colorado, Anschutz Medical Campus, Colorado.
²⁷ The Endocrine Society.

PMID: 31498871
PMCID: PMC6821450
DOI: 10.1210/jc.2019-01603

Abstract

This Position Statement has been endorsed by the International Menopause Society, The Endocrine Society, The European Menopause and Andropause Society, The International Society for Sexual Medicine, The International Society for the Study of Women's Sexual Health, The North American Menopause Society, The Federacion Latinoamericana de Sociedades de Climaterio y Menopausia, The Royal College of Obstetricians and Gynecologists, The International Society of Endocrinology, The Endocrine Society of Australia, and The Royal Australian and New Zealand College of Obstetricians and Gynecologists.

PubMed Disclaimer

Conflict of interest statement

Data sharing is not applicable to this article as no datasets were generated or analyzed during the current study.

Comment in

Response to Letter to the Editor: "Global Consensus Position Statement on the Use of Testosterone Therapy for Women".
Davis SR, Baber R, Panay N, Pinkerton J. Davis SR, et al. J Clin Endocrinol Metab. 2020 Jun 1;105(6):dgaa126. doi: 10.1210/clinem/dgaa126. J Clin Endocrinol Metab. 2020. PMID: 32160277 No abstract available.
Letter to the Editor: "Global Consensus Position Statement on the Use of Testosterone Therapy for Women".
Friedman AE. Friedman AE. J Clin Endocrinol Metab. 2020 Jun 1;105(6):dgaa118. doi: 10.1210/clinem/dgaa118. J Clin Endocrinol Metab. 2020. PMID: 32160280 No abstract available.

References

1. Islam MR, Bell RJ, Green S, Page M, Davis SR. Efficacy and safety of testosterone therapy for women: a systematic review and meta-analysis of randomized controlled trails. Lancet Diabetes Endocrinol. In press. - PubMed
1. Shekelle PG, Woolf SH, Eccles M, Grimshaw J. Developing clinical guidelines. West J Med. 1999;170(6):348–351. - PMC - PubMed
1. Davison SL, Bell R, Donath S, Montalto JG, Davis SR. Androgen levels in adult females: changes with age, menopause, and oophorectomy. J Clin Endocrinol Metab. 2005;90(7):3847–3853. - PubMed
1. Haring R, Hannemann A, John U, Radke D, Nauck M, Wallaschofski H, Owen L, Adaway J, Keevil BG, Brabant G. Age-specific reference ranges for serum testosterone and androstenedione concentrations in women measured by liquid chromatography-tandem mass spectrometry. J Clin Endocrinol Metab. 2012;97(2):408–415. - PubMed
1. Cappola AR, Ratcliffe SJ, Bhasin S, Blackman MR, Cauley J, Robbins J, Zmuda JM, Harris T, Fried LP. Determinants of serum total and free testosterone levels in women over the age of 65 years. J Clin Endocrinol Metab. 2007;92(2):509–516. - PubMed

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Global Consensus Position Statement on the Use of Testosterone Therapy for Women

Affiliations

Global Consensus Position Statement on the Use of Testosterone Therapy for Women

Authors

Affiliations

Abstract

Conflict of interest statement

Comment in

References

Publication types

MeSH terms

Substances

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical